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Mechanism of chronic dietary iron overload-induced liver damage in mice [J]

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Clinical Review by Gretchen Savery Gretchen Savery, Registered Psychotherapist (Qualifying), supports The Insight Clinics blog review and approval process by helping ensure content is accurate, thoughtful, and aligned with professional standards, including CRPO expectations around ethical communication, client confidentiality, and responsible mental health education

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Macrolide antibiotics such as troleandomycin, erythromycin, and erythromycin derivatives are metabolized, apparently by CYP3A, to metabolites that complex the cytochrome P450 heme iron and render it catalytically inactive

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et al., 2024) and zebrafish (Qian et al., 2025) suggesting a conserved disruption of dominant phyla across species in response to MPs exposure

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