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People with faster metabolisms process HHC more rapidly, leading to shorter detection windows, while slower metabolisms result in prolonged detectability

This is also supported by the fact that lung cancer is a frequent co-morbidity of COPD, a major inflammatory lung disease caused by smoke exposure

Macrophages pigmented smokers macrophages in respiratory bronchioles and neighbouring alveoli, containing granular, yellow-brown cytoplasmic pigments References and Links Barnes P , Mechanisms in COPD compared with asthma semantic Scholar Benjamin, R MD, MBA VADM, USPHS, Surgeon GeneralExposure to Tobacco Smoke Causes Immediate Damage: A Report of the Surgeon General Bohadana A et al Mechanisms of chronic airway obstruction in smokers Respiratory Medicine Volume 98, Issue 2, February 2004, Pages 139-151 TCV