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The nature of these interactions is likely also dependent upon the ability of the CTR ECD to adopt the conformation induced by the bypass motif of Amy-template peptides

Conversely, VRK2-low PC cells exhibit impaired SLC7A11 membrane localization and intrinsic oxidative stress, creating a therapeutic window for GSH inhibition

Collectively, tripeptides represent a promising class of multifunctional bioactive molecules in wound care, offering novel avenues for targeted tissue regeneration

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Third, we evaluated whether the molecules generated by the language model overlapped with an orthogonal set of enzymatic biotransformations of known metabolites that had been predicted in a rule-based manner by BioTransformer 23

These findings establish ferroptosis as a key mechanism in myoglobin-induced nephrotoxicity ( Figure 5 )