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Subsequent research indicated that the enhancement of MET by activating UPF1 (a versatile RNA and DNA helicase) caused phosphorylation, which, in turn, controlled the 3'-UTR length of STING, leading to a decrease in STING expression in cancer cells [123]

therefore, patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of EGRIFTA WR