Abbreviations COPD: Chronic obstructive pulmonary disease DDS: Drug delivery system ROS: Reactive oxygen species RNS: Reactive nitrogen species iNOS: Inducible nitric oxide synthase isoenzymes PM: Particulate matter SLPI: Secretory leukocyte protease inhibitor 1AT: Alpha-1-antitrypsin IL: Interleukin NF-B: Nuclear factor kappa B IL-8: Interleukin-8 GM-CSF: Granulocyte macrophage colony-stimulating factor SOD: Superoxide dismutase GPx: Glutathione peroxidase iNOS: Inducible nitric oxide synthase HDAC: Histone deacetylase EGFRs: Epithelial growth factor receptors BHR: Hyperresponsiveness P13K: Phosphoinositide 3-kinase TGF: Transforming growth factor MMP: Matrix metalloproteinase MUC5AC: Ne, neutrophil elastase TNF: Tumor necrosis factor CCL: CC-chemokine ligand CCR: CC-chemokine receptor CXCL: CXC-chemokine ligand CXCR: CXC-chemokine receptor T H 1: T helper1 cells T C 1: Type 1 cytotoxic NO: Nitric oxide ONOO : Peroxynitrite DPPC: L-a-dipalmitoylphosphatidyl-choline CAT: Catalase NAC: N-acetylcysteine TBARS: Thiobarbituric acid reactive species HBA: P-Hydroxybenzyl alcohol Trolox: Antioxidant and water-soluble analogue of Vitamin E Al 2 O 3 NPs: Aluminum oxide nanoparticles FP: Fluticasone propionate HPH: High-pressure homogenization PLGA: Poly(lactide-co-glycolide) PEG-DSPE: Polyethylene glycol and phosphatidylethanolamine PVP: Polyvinylpyrrolidone PVA: Polyvinyl alcohol PGA-co-PDL: Poly (glycerol adipate-co--pentadecalactone DOTAP: Dioleoyltrimethy- lammoniumpropane PLA: Poly(lactic acid) PEG: Polyethyleneglycol pHDAC2: HDAC2-encoding plasmid DNA MnPD: Mn-porphyrin dimer DESE: Double emulsion solvent evaporation method HPOX: HBA-incorporated copolyoxalate LPS: Lipopolysaccharide COX-2: Cyclooxygenase-2 U937: Human leukemic monocyte lymphoma cells CeNPs: Cationic cerium oxide nanoparticles CDs: Carbon dots SLNs: Soild lipid nanoparticles HPOX: Hydroxybenzyl alcohol-incorporated polyoxalate LPNs: Lipidpolymer hybrid nanoparticles SiO 2 NPs: Silica nanoparticles MABAs: Muscarinic antagonist and 2 agonist properties MMAD: Median mass aerodynamic diameter SFD: Supercritical fluid NCMPs: Nanocomposite microparticles MF: Mometasone furoate SX: Salmeterol xinafoate SBS: Salbutamol sulphate Nrf2: Dimethyl fumarate activator 2 BD: Budesonide RES: Resveratrol HA: Hyaluronic acid HSPB5: Alpha B-crystallin DEX: Dexamethasone PVAX: Polyvinyl alcohol-containing copolyoxalate HPH: High-pressure homogenization SX: Salmeterol Xinafoate FP: Fluticasone Propionate TPGS: D--tocopherol polyethylene glycol 1000 succinate BSA: Bovine serum albumin FPF: Fine particle fraction LPPs: Large porous microparticles SLMs: Solid lipid microparticles NCMPs: Nanocomposite microparticles PRINT: Particle Replication In Non-wetting Templates References Qaseem A, Wilt TJ, Weinberger SE, et al
Moreover, it is suggested that since it is a diet limiting the consumption of many food products, long-term adherence to KD may lead to nutritional deficiencies and consequences like anaemia and osteoporosis [Crosby et al ., 2021]
Glutathione assessment should always occur within a comprehensive medical evaluation, not in isolation
ACSL4 exacerbates ischemic stroke by promoting ferroptosis-induced brain injury and neuroinflammation
Levels of glutathione naturally decline as we age
Mitochondrial respiratory chain complexes I (NADH-CoQ reductase complex), II (succinate dehydrogenase complex), III (cytochrome bc-1 complex) can, under different metabolic stress, produce ROS that damage the mitochondrial membrane, resulting in lipid peroxidation and ultimately leading to ferroptosis
