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Clonogenic survival assays comparing the response to radiation in SCC-61, rSCC-61 and rSCC-61 with MTHFD2 knockdown further confirmed the function of this enzyme in the radiation resistance phenotype of rSCC-61 ( Figure 3C )

And I said, well, let's rinse some labs and see what's, what's going on

10.1038/nature09141 Nature 120 SheY.ShaoL.ZhangY.HaoY.CaiY.ChengZ.et al (2019)

8 Upon reduction of copper, the dioxygen product is immediately released (structure 3, figure above)

You gotta respect the tenacity of their products doing the talking, but I would still have liked to learn a bit more about them