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Recent research shows it alleviates inflammation in conditions like silicosis and ulcerative colitis by targeting pathways like SIRT1/STAT3, promoting tissue repair and reducing oxidative stress without systemic toxicity (10)

A significant focus was on developing inhibitors of insulin-regulated aminopeptidase (IRAP), a protein identified as the AT4 receptor, with the goal of enhancing metabolic stability and BBB permeability

Sharer JE, Shipley LA, Vandenbranden MR, Binkley SN, Wrighton SA

Multi-omics approaches, such as metabolomics to identify lipid peroxidation profiles and genomics to characterize polymorphisms in ferroptosis-regulating genes, may allow more accurate pathological classification

Their versatility in promoting healing, modulating biological processes, and serving as drug candidates positions them as essential tools in modern medicine, offering hope for more efficient treatments for a variety of conditions, including wounds, infections, and chronic diseases

Utilizing microwave-assisted extraction, active components such as GA were efficiently extracted from pomegranate peel