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It has also been shown that in addition to metabolic products, other external agents can have a prooxidant effect, which has led to the conclusion that lifestyle and diet can play an important role in controlling oxidative stress

Furthermore, the Cys15 and Cys170 residues could require a PAT for palmitoylation, and therefore would only be modified by palmitate within cells, and not in vitro

Ursodeoxycholic acid (UDCA) is a safe and effective treatment for cholestasis and can effectively treat 50% of primary biliary cholangitis patients

It is difficult for the body to excrete lipid-soluble molecules, and these compounds can easily cross cell membranes, affecting cellular activities

doi:10.1096/fj.09-132795

Radloff, L