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Finally, and perhaps the issue that is of greatest concern is that in addition to the unknown health effects, early evidence suggests that e-cigarette use may serve as an introductory product for youth who then go on to use other tobacco products, including conventional cigarettes, which are known to cause disease and lead to premature death

The leading cause of COPD is smoking

J Am Board Fam Med

2020 May;32(6):240-248

Noteworthy, a study has shown that those who tried to quit smoking but failed had higher odds of stress than those who did not try to quit 31

It can make childrens asthma symptoms more severe, leading to more symptomatic days and increased use of health care services, including hospitalizations