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In some cases deficiency is caused by an autoimmune disorder

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In vitro growth characteristics of melanocytes obtained from adult normal and vitiligo subjects

They exhibited reduced grip strength, and endurance, increased lactate levels and energy consumption, and muscle atrophy, including a reduction in slow muscle fiber levels

Finally, coenzyme Q 10 deficiency can be secondary to the inhibition of HMG-CoA reductase by statin drugs (see Deficiency)