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An in silico screening of a homology model of IRAP based on the crystal structure of LTA4H (Leukotriene-A4 hydrolase) was applied (Thunnissen et al., 2001)

2021 Oct 8;71:102917

[Tirzepatide] works on two hormone receptors and has been shown in clinical trials to be more effective than semaglutide. This comparison may have a lot riding on it given that tirzepatide is a drug manufactured by competitor Eli Lilly and Company