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277,278,279 When dysfunctional mitochondria cannot be cleared in time by mitophagy, damaged mitochondria accumulate, which results in insufficient energy supply as well as overproduced ROS, thereby triggering intense oxidative stress and cellular damage

It is located in the liver and is closely related to spleen and kidney functions

The objects of clinical physical examination include the breast, regional lymph nodes, and distant metastases

Neuroinflammation is the second major target

Acknowledgments We are grateful to the entire research group for their invaluable insights and camaraderie throughout this project

Typical cycle: 812 weeks