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Although often promoted as fat-burning aids , their primary clinical application is in supporting metabolic processes , especially when integrated into supervised weight loss programs

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Time-to- event analyses were performed using multivariable Cox-regression with time-varying exposure variable

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Conversely, senescence can also affect insulin signaling and glucose and lipid metabolism by reducing the expression or activity of insulin receptors or their substrates, increasing the levels of inflammatory cytokines or oxidative stress markers, impairing mitochondrial function or autophagy, or altering the composition or function of gut microbiota