Animal studies usually involve self-administration of nicotine, and are believed to rely on the same neurobiological mechanisms as human drug dependence
As far as the UK is concerned, Ridgway recommended that authorities review the evidence regarding the effectiveness of plain packaging and also consider governmental revenue losses as a result of the increasing illicit trade, which in the UK is now running at GBP2.8 billion per annum, or around GBP8 million a day, according to HMRC figures. If that happened, it also could throw a lifeline not only at tobacco businesses and associated industries, including marketing and engineering services using highly skilled employees
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