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Chronic smoking has been clearly shown to promote dysfunction of the BBB through activation of oxidative, inflammatory, and immune responses that support the onset and progression of cerebrovascular and neurodegenerative disorders, including TBI [21,22,23,24,25,26]

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Foreman had been raised in service, meaning he had worked as a house servant and was of peasant extraction

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It is often assumed that tinnitus is caused by damage to the ears