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In vivo studies Pulmonary toxicity A PMI study on chronic exposure of A/J Mice for 18 months to IQOS smoke showed that IQOS significantly reduced toxicity and carcinogenicity on red blood cell profile, liver function, lung inflammation, emphysematous, and histopathological changes compared to CS in respiratory tract organs 41

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To get to their destinations, their trucks use small and private roads to avoid tollgates, roadblocks, and ad-hoc searches by law enforcement on main roads 19 .Interview with clearing agent at Beitbridge Border Post, Beitbridge, April 2018

[6] [10] Duke set a deal with the Bonsack Machine Company in 1884