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doi: 10.1038/s41380-023-01979-3

(2015) Unconjugated Bilirubin Mediates Heme Oxygenase-1-Induced Vascular Benefits in Diabetic Mice

Several PET-based probes have been developed and tested to image iGluRs both in vitro and in vivo

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A clinical proof-of-concept trial used 0.03 mg/kg twice daily for short durations and found the drug to be generally well tolerated, though efficacy endpoints were mixed depending on the indication