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Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke

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"This variable is predictive and points to the negative impact of cannabis and cocaine on brain maturation, characterizing a worse prognosis for the addiction." Damage limitation for heroin addicts The use of substances such as methadone, an opioid, has been considered an effective harm reduction strategy as part of rehabilitation treatment for people addicted to heroin and other injectable drugs, achieving a measure of success in various countries since the 1990s