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The biggest reason why people relapse and start smoking again or chewing again is because something bad happens in their life, you know, they have some new stress or somebody dies or they lost their job or theyre getting a divorce, and then they start smoking again, because they cant handle those emotions, or they dont think they can without smoking. And the habit can be particularly difficult to kick for those who have been using nicotine since they were teenagers, Christensen added

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Increased oxidative stress, inflammatory cytokine production, and skin barrier disruption through multiple well-documented pathways