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doi:10.1002/anie.v62.22

The data demonstrated that diallyl sulfide showed the most suppressive effect on NO production and iNOS expression, suggesting that it was linked to the number of sulfur atoms of the organosulfur compounds

Nevertheless, limited by the poor cell permeability of itaconate, it is necessary to develop functionally similar itaconate derivatives (dimethyl itaconate [DMI] [177] and 4-octyl itaconate [4OI] [213]) or itaconate-loaded NMs