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Importin-beta: structural and dynamic determinants of a molecular spring

Inflammopharmacology 24 , 109118 (2016)

465 Recent research highlights the critical role of ZD in the progression of this condition

PMID 17969168

Tight and intricate regulatory processes maintain physiological H 2 S levels, while imbalances either in its production or breakdown have deleterious consequences, with high H 2 S levels eventually becoming toxic and/or pathogenic

This charge-neutralized resonance form has traditionally been accepted as the most important source of the catalytic power of PLP, and is certainly important to the mechanisms of PLP enzymes that require a stabilized carbanionic intermediate as a component of the reaction mechanism: AAT requires a stabilized carbanionic intermediate to achieve the 1,3-proton transfer