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Anthony Lanza, the assistant medical director of the Metropolitan Life Insurance Company, to soften his description of asbestosis as a disease similar to silicosis in the report that he submitted to the United States Public Health Service

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109 Activation of the inflammasome is responsible for the generation of active caspase-1, which cleaves a number of pro-inflammatory cytokines into their bio-active form, including IL-1, IL-18, and IL-33