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(Pharmacy compounding refers to combining different drug ingredients to create customized medications, such as doses of a specific strength or formulations without certain allergens.) Peptides can also fall in a regulatory gray area outside of these three categories

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10.1016/j.tibs.2015.11.012 13 BrashA

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Cureus , 13 (2), e13407

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Category D 34.1 Amino Acids, Complementary Medicine

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FDA on the 503A bulk substances Category 2 list in 2023 , removing it from compounding pharmacy eligibility on the grounds that human safety, immunogenicity, and PK data were insufficient

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A 2022 study on insomnia and oxidative stress highlighted the role of antioxidants in reducing sleep disturbances

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