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Epithalon has been shown to bind to promoter regions and alter chromatin structure in ways that may restore more youthful gene expression patterns

Effects of crystalline glucocorticoid triamcinolone acetonide on cultered human supraspinatus tendon cells

Bowman et al

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The presence of tumor stem cells is directly correlated with chemotherapy resistance in HGSOC, and these cells can evade drug effects through multiple mechanisms ( In our comprehensive exploration of HGSOC drug resistance mechanisms, we identified a complex and diverse biological foundation involving abnormalities in multiple cellular signaling pathways and alterations in the tumor microenvironment

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