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Biologic and targeted cell therapy Escalation to biologic or targeted cell therapy occurs when conventional options have failed or contraindications are present (e.g

testing should be targeted at individuals with: [15] Symptoms suggestive of deficiency Conditions affecting vitamin D metabolism (chronic kidney disease, malabsorption disorders) Increased fracture risk or metabolic bone disease Deficiency is generally defined as 25(OH)D levels below 25 nmol/L, with insufficiency between 2550 nmol/L

However, exclusive use of folic acid in treating vitamin B12 deficient megaloblastic anemia could result in progressive and irreversible neurologic damage

Approximately 44% were Caucasian, 19.1% were Asian, 4.3% were Indo-Canadian, 8.9% were African-Canadian, and 2.3% were Hispanic

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