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Patients undergoing evaluation for LT are particularly vulnerable to the systemic effects of tobacco, including its cardiovascular and renal implications [107]

The prevalence of phantosmia reaches a plateau at a time (about 8 weeks) were neuronal regeneration in the olfactory epithelium is likely to take place: indeed, regeneration time of a healthy epithelium after axotomy (including olfactory bulb reinnervation) is about 30 days in mammals [35, 36], but could be longer in a damaged epithelium

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Flavour and effect carry on for 20 to 60 minutes