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In answer to the more direct question of how much nicotine per day is safe, a reasonable starting point might be, "How much nicotine might it take to poison someone?" The ECHA currently gives an "acute toxicity estimate" (ATE) for nicotine via the oral route to be 5 mg/kg bw [7] , meaning 5mg of nicotine for every kilogram of bodyweight of the person consuming the nicotine

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Regardless of how much inhalation actually takes place, studies show that because cigar smoke dissolves more easily in saliva than cigarette smoke, cigar users absorb smoke and nicotine from cigars even when they report no inhalation

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