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Clinically used iron chelators such as Deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFS) are employed for treating transfusion iron overload in non-transfusion-dependent thalassemia patients [153, 154]

Studies also show that the glutathione antioxidant system plays an essential role in protecting the integrity of the gut barrier by attenuating enterocyte death 10

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So, there's one example where vaccination against sore mouth probably would have prevented a lot of trouble

Liao Z, Liu H, Swisher SG , Wang L, Wu TT, Correa AM, Roth JA, Cox JD, Komaki R, Ajani JA, Wei Q

The supernatant was aspirated and tubes were weighed again