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Identifying and functionally characterizing these microbial metabolites may lead to novel therapeutic strategies aimed at modulating the microbiome to mitigate disease risks and improve smoking cessation outcomes [144, 145]

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For example, over-the-counter nicotine replacement medicines (such as nicotine patches and nicotine gum) combined with specific types of counseling strategies (behavioral support, coping skills training) were effective at helping smokers to quit successfully

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Front Physiol 14:1236651