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[DOI] [PubMed] [Google Scholar] 145.Kalliafas S, Ziegler DW, Flancbaum L, Choban PS

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In that study, energy intake was not balanced between study groups but the links between BCAA catabolism and lipid oxidation reviewed here would suggest that the difference might not be due to caloric content of the two foods alone

The metabolites with altered levels in KOA or RA also included sulfur-containing AAs with essential roles in protein synthesis, structure, and folding [22]

Resulting metabolic changes (e.g., increased SAM) further alter methyltransferase activity, silencing additional tumor suppressors, which in turn amplifies metabolic dysregulation and oncogenic signaling