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Discussion: Overall, our data revealed that ENDS exposure exacerbates features of COPD in bENaC mice including emphysema, mucus accumulation, abnormal lung inflammation, and fibrosis, which involves the effect of COPD development by inducing ferroptosis in the lung

Those who did smoke were also taking up the habit later in life, except in four countries including Italy, where the number of children starting to smoke before reaching 13 had increased over the past decade

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The WHO's Dr Etienne Krug said e-cigarettes were fuelling a "new wave" of nicotine addiction