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If swollen lymph nodes are a result of an autoimmune disorder, they may shrink in size during periods of remission and then enlarge again when the illness flares up

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As CSE inhibits autophagosome maturation and degradation in macrophage like cells, and consequent intracellular and extracellular concentrations of galectin-8 are altered leading to the activation of pro-inflammatory signalling cascades, the galectin-8/NDP52 pathway may prove to be a novel therapeutic target in COPD

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