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Discussion In this nationally representative study of tobacco product use, cross-sectional analyses indicated that current exclusive cigarette use was associated with worse HRQoL compared to 5-year cigarette cessation, emphasizing negative physical and mental effects of continued cigarette exposure among people with COPD

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Evidence indicates lower exposure to toxic substances in HTPs than in conventional cigarettes 11

Those are ecto-hormones

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A general rule of thumb is to let a pipe rest for at least 24 hours after each smoke, though 48 hours is even better