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doi: 10.1089/thy.2019.0067 2 CaturegliPDe RemigisARoseNR

Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

Figure 1 For nearly as long as we have recognized PD, epidemiologic studies have suggested that extrinsic factors, including increasing age, male sex, environmental agent exposure, such as pesticide and chlorinated solvents exposure, unhealthy lifestyle, such as high dietary intake of dairy products, lower socioeconomic status, rural living, and traumatic brain injury (TBI), as well as intrinsic factors, including genetic predisposition, unusual metabolic states, and comorbidities such as diabetes, can be recognized as risk factors (Quik, 2004)

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CR was calculated up to 50% of the DEE and CR had to be maintained until the evening of day 1 (for timeline see Supplementary Fig

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