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The meta-analytic tool overcomes many of the limitations of traditional meta-analyses by incorporating between-study heterogeneity into the uncertainty of risk estimates, accounting for small numbers of studies, relaxing the assumption of log(linearity) applied to the risk functions, handling differences in exposure ranges between comparison groups, and systematically testing and adjusting for bias due to study designs and characteristics

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Paul warned that people will start selling menthol cigarettes illegally: Its supply and demand. That will make the community more vulnerable to police harassment, he said

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[140] A 2017 study found that "The maximum detected concentrations of benzene, methanol, and ethanol in the samples were higher than their authorized maximum limits as residual solvents in pharmaceutical products." [140] Trace amounts of toluene [114] and xylene have been found in the e-cigarette vapor