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At the same time, hepcidin levels increase, thereby accelerating the degradation of FPN, closing the iron transport outlet to the blood, and reducing the transport of iron from small intestinal epithelial cells and macrophages to the blood ( In addition, ferroptosis is closely related to iron metabolism under iron overload

Barinaga, M., Yamonoto, G., Rivier, C., Vale, W., Evans, R., Rosenfeld, M.G

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In hairless skin model, the extract of Reynoutria multiflora could up regulate SOD in a dose-dependent manner, thereby reducing UVB-induced oxidative damage, suggesting that the extract of Reynoutria multiflora contains anti skin photoaging agent (Hwang et al., 2006)

Some authors support the concept that oval cells may participate in the lineage of hepatocellular and cholangiocellular carcinomas and may serve as hepatic stem cells

M.Oliveira-AbreuK.Moreira-JuniorL.Santos-NascimentoT