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Progenesis QI TM employed median and means absolute deviation analysis based on all detected abundances to reduce bias and noise in the data 69

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344 nmol/mg, P =0.27)

LABs are inducers of reactive oxygen species (ROS) production in cultured cells and in vivo (59), inducing DNA damage in colon cells (60), which contrasts with LAB effects on the gastrointestinal tract

For example, co-exposure to arsenic and cadmium has been found to amplify oxidative stress and DNA damage beyond the effects of either compound alone, while simultaneous exposure to phthalates and bisphenol A enhances endocrine disruption and promotes oncogenic signaling cascades [261]

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