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doi: 10.1016/0165-6147(90)90235-z

[11] [25] Hemofiltration is more effective at removing large molecules from the bloodstream, such as myoglobin, [13] but this does not seem to confer any particular benefit

In chronic pain and depression, chronic exposure to stress is a common factor that may produce long-lasting changes (i.e., maladaptive neuroplasticity) in highly sensitive brain areas such as the prefrontal cortex and the hippocampus and in their functional connections, which may underlie the cognitive and behavioral impairments accompanying these conditions (Teffer and Semendeferi, 2012

In a clinical trial among COPD patients, significant improvement in forced expiratory volume (FEV1) occurred 5 minutes after dosing and continued to be evident through week 26 of treatment (D'Urzo 2011)

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