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The two stare at each other, mirror images

Like in the general population, in cEDS fatigue is multifactorial with contributing factors including articular pain, headache, sleep disturbance, and abnormally low blood pressure often associated with postural orthostatic tachycardia syndrome (POTS) or neurally mediated hypotension (NMH), nutritional deficiency, medications, and/or allergies (present in 32% of our patients) [80, 81, 87, 90,91,92,93,94,95]

We also appreciate the members of the Laboratory of Cell Biology and the Laboratory of Morphology and Image Analysis, Biomedical Research Core Facilities, Juntendo University Graduate School of Medicine, for technical assistance

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Cancer relapse under chemotherapy: why TLR2/4 receptor agonists can help