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During the last years, the utilization of patient stem cellbased high-throughput screening approaches and in silico prediction tools such as network mapping, genome-wide association studies, (GWAS) and rare variant association studies (RVAS) significantly accelerated the identification of candidate drugs for disease treatment

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These challenges highlight the need for more targeted approaches to modulate copper homeostasis in HF therapy

This review aims to elucidate the molecular mechanisms of essential oils at the cellular level

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