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and MIMS-iron, with pro-inflammatory molecular features, including increased expression of MHC class II, ferritin complex, FcY receptor for immunoglobulin, and complement C1 complex (C1QA and C1QB) expressing genes for ribosomal proteins, indicating a role in antigen presentation and perpetuation of inflammation (108)

J Physiol Biochem 69:897908

As an essential nitrogen source for nucleotide biosynthesis, endocytosed non-essential amino acid glutamine converts to glutamate and -ketoglutarate to contribute to anaplerosis [219]

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When the stress intensifies , by increasing its mode of action (increase in temperature, ozone concentration, salt content

It is also known to impact the activity of monoamine oxidase type enzymes, which influence neurotransmitter metabolism and may improve normal mitochondrial function