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Factors that contribute to higher smoking prevalence in Tobacco Nation include: Lower taxes , leading to a pack of cigarettes costing nearly 20% less in Tobacco Nation than in other states ($6.50 compared with $7.95) Lower spending on tobacco prevention and cessation programs , with less than 15% of recommended spending compared to 30% spent outside of Tobacco Nation Fewer comprehensive smoke-free policies , which cover 47% of Tobacco Nation residents compared to 64% of the rest of the U.S

In patients with HBV infection, smoking further increased the HCC risk by 1.4-fold, and even more dramatically, in individuals with HCV infection, the risk of HCC was increased 2.9-fold if there was a history of cigarette smoking [102]

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