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Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism

While its been popular in other countries around the world, demand stateside has recently grown, prompting the Food and Drug Administration to issue an advisory on injectable skin lightening agents

In fact, the Cu 2+ -histidine interaction (binding) in nature can match the importance of iron (Fe 2+ ) binding with proteins, and the consequent haem interactions that support the very existence of life (Walton et al., 2023)