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Drug resistance in LSCs is a naturally occurring trait and is more dependent on their intrinsic biological properties which endow them with stronger genetic and epigenetic stability (43)

Shan L, Molberg O, Parrot I, et al

Beauchamp E, et al

The use of oral vitamin C in this way was motivated by its widespread use, limited oral absorption (59), and inability to reach anywhere near the supratherapeutic concentrations which have shown promise in EBV CFS patients (60) or acute COVID inpatients (61)

For now, that remains a research question rather than a clinical recommendation

Supports detoxification and antioxidant defense