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Succination of Keap1 and activation of Nrf2-dependent antioxidant pathways in FH-deficient papillary renal cell carcinoma type 2

It may also have the potential to improve skin elasticity and reduce skin wrinkles

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

Stem Cells 33(7):23062319

McElvaney OJ, Curley GF, Rose-John S, McElvaney NG

These mutations lead to constitutive activation of Ras, resulting in persistent activation of the MAPK pathway, promoting uncontrolled cell proliferation and survival