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Low-dose metformin reprograms the tumor immune microenvironment in human esophageal cancer: results of a phase II clinical trial

* These proteins accelerate chemical reactions converting food substances to be easily absorbed in the digestive tract

Among all the functions, anti-oxidant defence of GSH is the most significant one [39]

TNNT2, troponin T, cardiac muscle, GSTM2, glutathione S-transferase Mu 2

Willis, R

Central to this interaction is cytochrome P450 2E1 (CYP2E1), whose induction by both ethanol and insulin resistance enhances oxidative stress, lipid peroxidation, and fibrogenesis