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In massive acute cyanide poisoning, the mechanism of toxicity may involve other enzyme systems as well

Similarly, a review with five RCTs (449 participants) also found that 84% of individuals receiving acupuncture experienced a reduction in symptom severity, in contrast to 63% of those undergoing pharmacological treatment, indicating that acupuncture was significantly more efficacious than either pharmacological therapy or no targeted intervention [121]

From a translational perspective, uncertainty in pharmacokinetic comparability remains a central limitation

However, when they become consistent rather than occasional, it is worth paying attention

The debate has exposed an uncomfortable problem

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