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ARTDs were shown to be involved in DNA repair and stress responses, cell signaling, transcription regulation, apoptosis, cell differentiation, maintenance of genomic integrity, and antiviral defense (reviewed in 8)

The FDA classifies all electronic nicotine delivery systems (ENDS) and broadly most vapor devices as tobacco products , regardless of nicotine content

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Women who are exposed to secondhand smoke may experience reduced ovarian reserve and irregular menstrual cycles, similar to active smokers

Broader retail trend coverage also points in this direction