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The highest dose (1:8) prevented acidosis, however three of eight animals died

Other Lipid Mediat 98, 110

Moderate levels of vitamin D may also helpcontroldisease activity

Fosmanogepix (E1210/APX001), a broad-spectrum antifungal agent with a novel mechanism of action (inhibition of fungal glycosylphosphatidylinositol-insulin glucose biosynthesis), which has shown efficacy in IA animal models (Shaw and Ibrahim, 2020)