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Nicotine is the main culprit, but smoking habits also play a role

These patterns underscore the importance of considering smoking status when interpreting treatment outcomes and planning long-term management, particularly given more recent evidence that smoking may influence disease activity even among patients receiving oral disease-modifying therapies such as fingolimod and dimethyl fumarate (95)

With some conditions, such as patchy hair loss , hair may regrow without treatment within a year

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